A. Create an AWS Organizations SCP that denies access to all non-global services in non-US Regions. Attach the policy to the root of the organization. Most Voted
B. Configure AWS CloudTrail to send logs to Amazon CloudWatch Logs and enable it for all Regions. Use a CloudWatch Logs metric filter to send an alert on any service activity in non-US Regions. Most Voted
C. Use an AWS Lambda function that checks for AWS service activity and deploy it to all Regions. Write an Amazon EventBridge rule that runs the Lambda function every hour, sending an alert if activity is found in a non-US Region.
D. Use an AWS Lambda function to query Amazon Inspector to look for service activity in non-US Regions and send alerts if any activity is found.
E. Write an SCP using the aws:RequestedRegion condition key limiting access to US Regions. Apply the policy to all users, groups and roles.

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